Recombinant Human TENT5C Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TENT5C-3074H
• Product Overview: FAM46C MS Standard C13 and N15-labeled recombinant protein (NP_060179) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase which enhances mRNA stability and gene expression. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein and may be involved in induction of cell death.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 44.9 kDa
• AA Sequence: MAEESSCTRDCMSFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKVCTDTDRWSLISLSNKNGKNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSNNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPTDQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPSATNVTCYYQPAPYVSDGNFSNYYVAHPPVTYSQPYPTWLPCNTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TENT5C terminal nucleotidyltransferase 5C [ Homo sapiens (human) ]
• Official Symbol: TENT5C
• Synonyms: TENT5C; terminal nucleotidyltransferase 5C; FAM46C; terminal nucleotidyltransferase 5C; family with sequence similarity 46 member C; non-canonical poly(A) polymerase FAM46C; protein FAM46C; putative nucleotidyltransferase FAM46C; EC 2.7.7.19
• Gene ID: 54855
• mRNA Refseq: NM_017709
• Protein Refseq: NP_060179
• MIM: 613952
• UniProt ID: Q5VWP2