Recombinant Human SYNE2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SYNE2-1644H
• Product Overview: SYNE2 MS Standard C13 and N15-labeled recombinant protein (NP_878914) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 48 kDa
• AA Sequence: MEGDRNVPPVPPASSTPYKPPYGKLLLPPGTDGGKEGPRVLNGNPQQEDGGLAGITEQQSGAFDRWEMIQAQELHNKLKIKQNLQQLNSDISAITTWLKKTEAELEMLKMAKPPSDIQEIELRVKRLQEILKAFDTYKALVVSVNVSSKEFLQTESPESTELQSRLRQLSLLWEAAQGAVDSWRGGLRQSLMQCQGSKTRPRSDVLFFKDFHQLSQNLLLWLASAKNRRQKAHVTDPKADPRALLECRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPAPRAKFRAVRTTEGEEETESRVPGSTRPQRSFLSRVVRAALPLQLLLLLLLLLACLLPSSEEDYSCTQANNFARSFYPMLRYTNGPPPTTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SYNE2 spectrin repeat containing nuclear envelope protein 2 [ Homo sapiens (human) ]
• Official Symbol: SYNE2
• Synonyms: SYNE2; spectrin repeat containing, nuclear envelope 2; nesprin-2; DKFZP434H2235; KIAA1011; Nesprin 2; NUA; NUANCE; SYNE 2; nesprin 2; polytrophin; synaptic nuclei expressed gene 2; synaptic nuclear envelope protein 2; nuclear envelope spectrin repeat protein 2; nucleus and actin connecting element protein; EDMD5; TROPH; SYNE-2; Nesprin-2; FLJ11014; FLJ43727; FLJ45710; FLJ46790; DKFZp434H2235; DKFZp686H1931; DKFZp686E01115
• Gene ID: 23224
• mRNA Refseq: NM_182910
• Protein Refseq: NP_878914
• MIM: 608442
• UniProt ID: Q8WXH0