Recombinant Human Syndecan Binding Protein (Syntenin), His-tagged

• Cat.No.: SDCBP-3367H
• Product Overview: Recombinant human SDCBP protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 34.6kDa(318aa).

Specification

• Cat. No.: SDCBP-3367H
• Description: SDCBP, also known as Syntenin1, is a multifunctional intracellular adapter protein. This protein contains tandemly repeated PDZ domains that react with the FYA (phe-tyr-ala) carboxyterminal amino acid sequence of the syndecans. It is involved in organization of protein complexes in the plasma membranes, regulation of B-cell development, activation of transcription factors, intracellular trafficking and cell-surface targeting, synaptic transmission, and axonal outgrowth.
• Source: E.coli.
• Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 40% Glycerol.
• Purity: > 90% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSE ASAPIP HDGNLYPRLY PELSQYMGLS LNEEEIRANVAVVSGAPLQG QLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQAN SPASLV GLRFGDQVLQINGENCAGWS SDKAHKVLKQ AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN GLLTEHNICE INGQ NVIGLKD SQIADILST SGTVVTITIM PAFIFEHIIK RMAPSIMKSL MDHTIPEV.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Fuction: cytoskeletal adaptor activity; frizzled binding; protein N-terminus binding; interleukin-5 receptor binding; protein heterodimerization activity; syndecan binding
• Pathways: Axon guidance

Gene Information

• Gene Name: SDCBP syndecan binding protein (syntenin) [ Homo sapiens ]
• Synonyms: syndecan binding protein (syntenin); ST1; SYCL; MDA-9; TACIP18; SDCBP; syntenin-1; scaffold protein Pbp1; syndecan-binding protein 1; melanoma differentiation associated protein-9; melanoma differentiation-associated protein 9; pro-TGF-alpha cytoplasmic domain-interacting protein 18; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Scaffold protein Pbp1; Melanoma differentiation-associated protein 9; Syndecan-binding protein 1; MDA9
• Gene ID: 6386
• mRNA Refseq: NM_001007067
• Protein Refseq: NP_001007068
• MIM: 602217
• UniProt ID: O00560
• Chromosome Location: 8q12