Recombinant Human SYK Protein, His-FLAG-tagged

• Cat.No.: SYK-109H
• Product Overview: Recombinant human full length SYK protein (1-635 aa) was expressed in HEK 293 cells with an N-terminal His-Flag tag

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: 1-635 a.a.
• Description: Spleen Tyrosine Kinase (SYK) belongs to the family of non-receptor type Tyr protein kinases. The SYK protein is extensively expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events which mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis.
• Form: Liquid
• Molecular Mass: 74.25kDa.
• AA sequence: MHHHHHHDYKDDDDKKLMASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGL YLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQES DGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQL EKLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKV LHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFG GRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELA PWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTV KKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES WMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARN VLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVW SFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWT YDVENRPGFAAVELRLRNYYYDVVN
• Purity: >85.0% as determined by SDS-PAGE.
• Storage: Store at 4 centigrade if entire vial will be used within 2-4 weeks. Store, frozen at -20 centigrade for longer periods of time. Please avoid freeze thaw cycles.
• Storage buffer: 50mM Tris pH 7.5, 300mM NaCl and 10% Glycerol.
• Full Length: Full L.

Gene Information

• Gene Name: SYK spleen tyrosine kinase [ Homo sapiens ]
• Official Symbol: SYK
• Synonyms: SYK; spleen tyrosine kinase; tyrosine-protein kinase SYK; p72-Syk; FLJ25043; FLJ37489; DKFZp313N1010
• Gene ID: 6850
• mRNA Refseq: NM_001135052
• Protein Refseq: NP_001128524
• MIM: 600085
• UniProt ID: P43405