Recombinant Human superoxide dismutase 3, extracellular Protein, HA tagged

• Cat.No.: SOD3-59H
• Product Overview: Recombinant Human SOD3 Protein with C-HA and N-Glu-Ala was expressed in Yeast (animal free media and environment).

Specification

• Description: This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk.
• Source: Yeast
• Species: Human
• Tag: C-HA; N-Glu-Ala
• Form: Lyophilized
• Molecular Mass: 25.5 kDa
• AA Sequence: (EA)WTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAAYPYDVPDYA
• Endotoxin: < 0.2 EU/μg of protein as determined by the LAL method.
• Purity: 0.98
• Storage: Stable for at least one year at -20 centigrade. Upon reconstitution HSA can be stored at +4 centigrade for 1 day or at -20 centigrade for 6 months.
• Concentration: 100 μg/μL
• Storage Buffer: Phosphate -buffered saline (PBS), pH 7.4
• Reconstitution: Spin the vial briefly, add distilled sterile water.

Gene Information

• Gene Name: SOD3 superoxide dismutase 3, extracellular [Homo sapiens (human)]
• Official Symbol: SOD3
• Synonyms: SOD3; superoxide dismutase 3, extracellular; extracellular superoxide dismutase [Cu-Zn]; EC SOD; EC-SOD; MGC20077
• Gene ID: 6649
• mRNA Refseq: NM_003102
• Protein Refseq: NP_003093
• MIM: 185490
• UniProt ID: P08294