Recombinant Human SUOX, MYC/DDK-tagged

• Cat.No.: SUOX-192H
• Product Overview: Recombinant Human SUOX, transcript variant 1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
• Molecular Mass: 60.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: SUOX sulfite oxidase [ Homo sapiens (human) ]
• Official Symbol: SUOX
• Synonyms: SUOX; sulfite oxidase; sulfite oxidase, mitochondrial; NP_000447.2; EC 1.8.3.1; NP_001027558.1; NP_001027559.1
• Gene ID: 6821
• mRNA Refseq: NM_000456
• Protein Refseq: NP_000447
• MIM: 606887
• UniProt ID: P51687
• Chromosome Location: 12q13.2
• Pathway: Degradation of cysteine and homocysteine; Metabolism of amino acids and derivatives; Sulfur amino acid metabolism
• Function: electron carrier activity; heme binding; molybdenum ion binding; molybdopterin cofactor binding