Recombinant Human STEAP3 protein, MYC/DDK-tagged

• Cat.No.: STEAP3-16H
• Product Overview: Recombinant Human STEAP3, transcript variant 3, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 54.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: STEAP3 STEAP family member 3, metalloreductase [ Homo sapiens ]
• Official Symbol: STEAP3
• Synonyms: STMP3; TSAP6; dudlin-2
• Gene ID: 55240
• mRNA Refseq: NM_001008410
• Protein Refseq: NP_001008410
• MIM: 609671
• UniProt ID: Q658P3
• Chromosome Location: 2q14.2
• Pathway: Direct p53 effectors, organism-specific biosystem;Iron uptake and transport, organism-specific biosystem;Transferrin endocytosis and recycling, organism-specific biosystem;Transmembrane transport of small molecules, organism-specific biosystem;p53 signaling pathway, organism-specific biosystem;p53 signaling pathway, conserved biosystem
• Function: ferric-chelate reductase activity;metal ion binding;nucleotide binding;protein binding