Recombinant Human STC1 Protein, DDK/His-tagged

• Cat.No.: STC1-578H
• Product Overview: Recombinant Human STC1(Thr34-Ala247) fused with DDK/His tag at C-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: 34-247 a.a.
• Description: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
• Form: 1 x PBS, pH7.4, 10% glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 26 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: STC1 stanniocalcin 1 [ Homo sapiens ]
• Official Symbol: STC1
• Synonyms: STC1; stanniocalcin 1; STC; stanniocalcin-1
• Gene ID: 6781
• mRNA Refseq: NM_003155
• Protein Refseq: NP_003146
• MIM: 601185
• UniProt ID: P52823