Recombinant Human STAT6 Protein, His-tagged

Cat.No. : STAT6-151H
Product Overview : Recombinant Human signal transducer and activator of transcription 6, interleukin-4 induced(STAT6) protein, transcript variant 2(NM_003153), with a His tag, was expressed in human cells.
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Species : Human
Source : Human Cells
Tag : His
Description : The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.31, without any preservatives.
Molecular Mass : 23.9kD
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name STAT6 signal transducer and activator of transcription 6, interleukin-4 induced [ Homo sapiens ]
Official Symbol STAT6
Synonyms STAT6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and activator of transcription 6; D12S1644; IL 4 STAT; STAT, interleukin4-induced; transcription factor IL-4 STAT; STAT6B; STAT6C; IL-4-STAT;
Gene ID 6778
mRNA Refseq NM_001178078
Protein Refseq NP_001171549
MIM 601512
UniProt ID P42226

Not For Human Consumption!

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