Recombinant Human STAT6 Protein, His-tagged
Cat.No. : | STAT6-151H |
Product Overview : | Recombinant Human signal transducer and activator of transcription 6, interleukin-4 induced(STAT6) protein, transcript variant 2(NM_003153), with a His tag, was expressed in human cells. |
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Species : | Human |
Source : | Human Cells |
Tag : | His |
Description : | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.31, without any preservatives. |
Molecular Mass : | 23.9kD |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name | STAT6 signal transducer and activator of transcription 6, interleukin-4 induced [ Homo sapiens ] |
Official Symbol | STAT6 |
Synonyms | STAT6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and activator of transcription 6; D12S1644; IL 4 STAT; STAT, interleukin4-induced; transcription factor IL-4 STAT; STAT6B; STAT6C; IL-4-STAT; |
Gene ID | 6778 |
mRNA Refseq | NM_001178078 |
Protein Refseq | NP_001171549 |
MIM | 601512 |
UniProt ID | P42226 |
◆ Recombinant Proteins | ||
STAT6-344H | Recombinant Human STAT6 protein, His/MBP-tagged | +Inquiry |
STAT6-30854TH | Recombinant Human STAT6, His-tagged | +Inquiry |
STAT6-151H | Recombinant Human STAT6 Protein, His-tagged | +Inquiry |
STAT6-6368H | Recombinant Human STAT6 Protein (Ser627-Ser837), C-His tagged | +Inquiry |
STAT6-4889H | Recombinant Human Signal Transducer And Activator Of Transcription 6, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
STAT6-481HCL | Recombinant Human STAT6 cell lysate | +Inquiry |
Not For Human Consumption!
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