Recombinant Human STAT5a, His-tagged

• Cat.No.: STAT5A-01H
• Product Overview: A DNA sequence encoding Human STAT5A ( a.a.129-712 ) was fused with a His tag .

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 129-712 a.a.
• Form: 20 mM Tris-HCl, 200 mM NaCl, pH7.4
• Molecular Mass: ~67kDa
• AA Sequence: PAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLSPQERLSRETA LQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSW CEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVR LLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRAD RRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVL WPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVM EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSI RSLADRLGDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASAD
• Purity: >92% as determined by SDS-PAGE
• Storage: Short Term Storage +4°C. Long Term Storage -20°C. Prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: STAT5A signal transducer and activator of transcription 5A [ Homo sapiens ]
• Official Symbol: STAT5A
• Synonyms: STAT5A; signal transducer and activator of transcription 5A; STAT5; MGF
• Gene ID: 6776
• mRNA Refseq: NM_003152
• Protein Refseq: NP_003143
• MIM: 601511
• UniProt ID: P42229
• Chromosome Location: 17q11.2
• Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adipogenesis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chronic myeloid leukemia, organism-specific biosystem
• Function: RNA polymerase II core promoter sequence-specific DNA binding; calcium ion binding; double-stranded DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity