Recombinant Human STARD4 Protein, MYC/DDK-tagged

• Cat.No.: STARD4-2900H
• Product Overview: Recombinant Human STARD4 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 23.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: STARD4 START domain containing 4 [ Homo sapiens ]
• Official Symbol: STARD4
• Synonyms: 4632419C16Rik; 9030213J02Rik; AA517649; AW324468; StAR-related lipid transfer protein 4; StAR-related lipid transfer (START) domain containing 4
• Gene ID: 154899
• mRNA Refseq: NM_139164.2
• Protein Refseq: NP_631903