Recombinant Human STAR Protein, MYC/DDK-tagged

• Cat.No.: STAR-2903H
• Product Overview: Recombinant Human STAR protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 29.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: STAR steroidogenic acute regulatory protein [ Homo sapiens ]
• Official Symbol: STAR
• Synonyms: STARD1;StAR-related lipid transfer (START) domain containing 1; START domain containing 1; cholesterol trafficker; mitochondrial steroid acute regulatory protein; steroid acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regula
• Gene ID: 6770
• mRNA Refseq: NM_000349
• Protein Refseq: NP_000340
• MIM: 600617
• UniProt ID: P49675