Recombinant Human SRM, His-tagged

Cat.No. : SRM-30397TH
Product Overview : Recombinant full length Human Spermidine synthase with an N terminal His tag. Predicted mwt: 36 kDa.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 302 amino acids
Description : The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
Conjugation : HIS
Molecular Weight : 36.000kDa inclusive of tags
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MEPGPDGPAA SGPAAIREGW FRETCSLWPG QALSLQVEQL LHHRRSRYQD ILVFRSKTYG NVLVLDGVIQ CTERDEFSYQ EMIANLPLCS HPNPRKVLII GGGDGGVLRE VVKHPSVESV VQCEIDEDVI QVSKKFLPGM AIGYSSSKLT LHVGDGFEFM KQNQDAFDVI ITDSSDPMGP AESLFKESYY QLMKTALKED GVLCCQGECQ WLHLDLIKEM RQFCQSLFPV VAYAYCTIPT YPSGQIGFML CSKNPSTNFQ EPVQPLTQQQ VAQMQLKYYN SDVHRAAFVL PEFARKALND VS
Sequence Similarities : Belongs to the spermidine/spermine synthase family.
Gene Name SRM spermidine synthase [ Homo sapiens ]
Official Symbol SRM
Synonyms SRM; spermidine synthase; SRML1; SPS1;
Gene ID 6723
mRNA Refseq NM_003132
Protein Refseq NP_003123
MIM 182891
Uniprot ID P19623
Chromosome Location 1p36-p22
Pathway Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Glutathione metabolism, organism-specific biosystem;
Function protein homodimerization activity; spermidine synthase activity; transferase activity;

Not For Human Consumption!

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