Recombinant Human SPN, His-tagged
Cat.No. : | SPN-2310H |
Product Overview : | Recombinant human SPN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 257aa |
Description : | SPN is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 25.8kDa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSSTTAVQT PTSGEPLVST SEPLSSKMYT TSITSDPKAD STGDQTSALP PSTSINEGSP LWTSIGASTGSPLPEPTTYQ EVSIKMSSVP QETPHATSHP AVPITANSLG SHTVTGGTIT TNSPETSSRT SGAPVTTAAS SLETSRGTSG PPLTMATVSLETSKGTSGPP VTMATDSLET STGTTGPPVT MTTGSLEPSS GASGPQVSSV KLSTMMSPTT STNASTVPFR NPDENSR |
Purity : | >85% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml |
Gene Name | SPN sialophorin [ Homo sapiens ] |
Official Symbol | SPN |
Synonyms | SPN; sialophorin; sialophorin (gpL115, leukosialin, CD43); leukosialin; CD43; GPL115; LSN; GALGP; galactoglycoprotein; leukocyte sialoglycoprotein; sialophorin (leukosialin, CD43); |
Gene ID | 6693 |
mRNA Refseq | NM_001030288 |
Protein Refseq | NP_001025459 |
MIM | 182160 |
UniProt ID | P16150 |
Chromosome Location | 16p11.2 |
Pathway | Basigin interactions, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function | bacterial cell surface binding; binding; transmembrane signaling receptor activity; |
◆ Recombinant Proteins | ||
SPN-2310H | Recombinant Human SPN, His-tagged | +Inquiry |
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Spn-6565M | Recombinant Mouse Spn protein, His-tagged | +Inquiry |
SPN-2685H | Recombinant Human SPN Protein, MYC/DDK-tagged | +Inquiry |
Spn-7035MP | Recombinant Mouse Spn protein, Fc-tagged, R-PE labeled | +Inquiry |
◆ Cell & Tissue Lysates | ||
SPN-893RCL | Recombinant Rat SPN cell lysate | +Inquiry |
SPN-1739MCL | Recombinant Mouse SPN cell lysate | +Inquiry |
Not For Human Consumption!
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