Recombinant Human SPINDOC Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SPINDOC-3056H
• Product Overview: C11orf84 MS Standard C13 and N15-labeled recombinant protein (NP_612480) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway. Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 41 kDa
• AA Sequence: MALKAEGAALDCFEVTLKCEEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDWPTVLSESSTTVAGKPEKGNGVTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SPINDOC spindlin interactor and repressor of chromatin binding [ Homo sapiens (human) ]
• Official Symbol: SPINDOC
• Synonyms: SPINDOC; spindlin interactor and repressor of chromatin binding; C11orf84; SPIN-DOC; spindlin interactor and repressor of chromatin-binding protein; SPIN1 docking protein; hypothetical protein BC007540; uncharacterized protein C11orf84
• Gene ID: 144097
• mRNA Refseq: NM_138471
• Protein Refseq: NP_612480
• UniProt ID: Q9BUA3