Recombinant Human SOST protein, His-Avi-tagged

• Cat.No.: SOST-471H
• Product Overview: Human SOST/Sclerostin Protein is expressed from mammalian with a Poly-His and Avi Tag at the N-terminal. It contains Gln 24 - Tyr 213.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: It contains Gln 24 - Tyr 213.
• Description: SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The Human SOST/Sclerostin Protein has a calculated MW of 24.2kDa. As a result of glycosylation, the protein migrates as 25-40 kDa under reducing (R) condition (Bis-Tris PAGE).
• Endotoxin: Less than 0.1 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: SOST sclerostin [ Homo sapiens ]
• Official Symbol: SOST
• Synonyms: sclerostin; SOST; VBCHsclerosteosis
• Gene ID: 50964
• mRNA Refseq: NM_025237
• Protein Refseq: NP_079513
• MIM: 605740
• UniProt ID: Q9BQB4