Recombinant Human SNRPG, His-tagged

• Cat.No.: SNRPG-3507H
• Product Overview: Recombinant human SNRPG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Small nuclear ribonucleoprotein polypeptide G, also known as SNRPG, belongs to the snRNPSm proteins family. There are at least seven isoforms, B/B, E, F, G, D1, D2, and D3. This class of common proteins plays an essential role in the biogenesis of the snRNPs. The genes encoding human Sm G map to chromosomes 2. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE). One class of these autoantibodies reacts specifically with native Sm E-F-G complexes.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.1M NaCl
• Molecular Weight: 10.6 kDa (96aa), confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSKAHPPELK KFMDKKLSLK LNGGRHVQGI LRGFDPFMNLVIDECVEMAT SGQQNNIGMV VIRGNSIIMLEALERV
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: SNRPG small nuclear ribonucleoprotein polypeptide G[ Homo sapiens ]
• Synonyms: small nuclear ribonucleoprotein polypeptide G; SMG; Sm-G; MGC117317; SNRPG; snRNP-G; sm protein G;OTTHUMP00000204047; OTTHUMP00000204048;OTTHUMP00000204050; PBSCG
• Gene ID: 6637
• mRNA Refseq: NM_003096
• Protein Refseq: NP_003087
• MIM: 603542
• UniProt ID: P62308
• Chromosome Location: 2p13.3
• Function: RNA binding; protein binding