Recombinant Human SMS, His-tagged

• Cat.No.: SMS-30398TH
• Product Overview: Recombinant full length Human Spermine synthase with N terminal His tag; 390 amino acids with tag, Predicted MWt 43.8 kDa.

Specification

• Description: The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism.
• Protein length: 366 amino acids
• Conjugation: HIS
• Molecular Weight: 43.800kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 0.02% DTT, 10% Glycerol, 0.58% Sodium chloride
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSHMAAARHSTLDFMLGAK ADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNG SFANLRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEER MKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDI DEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLA YTRAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMV TMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDC IPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLR LILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLY CPVEFSKEIVCVPSYLELWVFYTVWKKAKP
• Sequence Similarities: Belongs to the spermidine/spermine synthase family.

Gene Information

• Gene Name: SMS spermine synthase [ Homo sapiens ]
• Official Symbol: SMS
• Synonyms: SMS; spermine synthase; Snyder Robinson X linked mental retardation syndrome , SRS; MRSR; SPMSY; SpS
• Gene ID: 6611
• mRNA Refseq: NM_004595
• Protein Refseq: NP_004586
• MIM: 300105
• Uniprot ID: P52788
• Chromosome Location: Xp22.1
• Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Glutathione metabolism, organism-specific biosystem
• Function: spermidine synthase activity; spermine synthase activity; transferase activity