Recombinant Human SLURP1 Protein (Met1-Leu103), His tagged

Description :	Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca2+ signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation.
Source :	E. coli
Species :	Human
Tag :	His
Form :	Lyophilized powder/frozen liquid
Molecular Mass :	13.09 kDa
Protein length :	Met1-Leu103
Purity :	>90% as determined by SDS-PAGE.
Notes :	For research use only.
Storage :	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer :	Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
Reconstitution :	Reconstitute in sterile water for a stock solution.
Shipping :	They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Name	SLURP1 secreted LY6/PLAUR domain containing 1 [ Homo sapiens (human) ]
Official Symbol	SLURP1
Synonyms	SLURP1; secreted LY6/PLAUR domain containing 1; secreted Ly-6/uPAR-related protein 1; ANUP; ARS; ARS component B; ArsB; LY6LS; lymphocyte antigen 6 like secreted; MDM; SLURP-1; ARS (component B) -81/S; anti-neoplastic urinary protein; lymphocyte antigen 6-like secreted; secreted Ly6/uPAR related protein 1;
Gene ID	57152
mRNA Refseq	NM_020427
Protein Refseq	NP_065160
MIM	606119
UniProt ID	P55000