Recombinant Human SLC30A10 Protein (G2-F485), 8×His-Strep, Flag tagged

Cat.No. : SLC30A10-0830H
Product Overview : Recombinant Human 8His-Strep II-TEV-(GG)- SLC30A10(G2-F485)-Flag Protein was expressed in Insect cell.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. However, elevated levels of manganese are cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Acts as manganese efflux transporter and confers protection against manganese-induced cell death. Also acts as zinc transporter involved in zinc homeostasis. Seems to mediate zinc transport into early endosomes and recycling endosomes to prevent zinc toxicity; the function may be regulated by heterodimerization with other zinc transporters of the SLC30A subfamily. The SLC30A3:SLC30A10 heterodimer is involved in zinc transport-dependent regulation of the EGFR/ERK transduction pathway in endosomes. May be involved in regulation of zinc-dependent senescence of vascular smooth muscle cells.
Source : Insect cell
Species : Human
Tag : His&Flag&Strep
Form : Liquid
Protein length : G2-F485
Endotoxin : < 0.01 EU per μg of the protein
Purity : 90%
Stability : Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Formulation:
Shipping : It is shipped out with blue ice.
Gene Name SLC30A10 solute carrier family 30 member 10 [ Homo sapiens (human) ]
Official Symbol SLC30A10
Synonyms SLC30A10; solute carrier family 30 member 10; ZNT8; ZRC1; HMDPC; ZNT10; ZnT-10; HMNDYT1; zinc transporter 10; manganese transporter SLC30A10; zinc resistance conferring homolog; zinc transporter 8
Gene ID 55532
mRNA Refseq NM_018713
Protein Refseq NP_061183
MIM 611146
UniProt ID Q6XR72

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All SLC30A10 Products

Required fields are marked with *

My Review for All SLC30A10 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon