Recombinant Human SLAMF6 Protein (Gln22-Met226), C-mFc and 6×His-tagged

• Cat.No.: SLAMF6-671H
• Product Overview: Recombinant Human SLAMF6 Protein (Gln22-Met226) with C-mFc and 6×His tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Source: HEK293
• Species: Human
• Tag: His&mFc
• Form: Lyophilized
• Molecular Mass: 50.1 kDa
• Protein length: Gln22-Met226
• Purity: > 95% as determined by SDS-PAGE and Coomassie blue staining.
• Storage: Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing)
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 50 % trehalose is added as protectants before lyophilization.

Gene Information

• Gene Name: SLAMF6 SLAM family member 6 [ Homo sapiens (human) ]
• Official Symbol: SLAMF6
• Synonyms: SLAMF6; SLAM family member 6; CD352; KALI; KALIb; Ly108; NTB A; NTBA; SF200; NTBA receptor; NK-T-B-antigen; activating NK receptor; natural killer-, T- and B-cell antigen; NTB-A; FLJ50657; MGC104953
• Gene ID: 114836
• mRNA Refseq: NM_001184714
• Protein Refseq: NP_001171643
• MIM: 606446
• UniProt ID: Q96DU3