Recombinant Human SIGLEC5 Protein, hIgG-His-Tagged

• Cat.No.: SIGLEC5-01H
• Product Overview: Recombinant Human SIGLEC5 Protein, hIgG-His-Tagged was expressed in Baculovirus cell line

Specification

• Description: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
• Source: Baculovirus
• Species: Human
• Tag: His&Fc
• Form: Liquid
• Molecular Mass: 74.2 kDa
• Protein length: 667aa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Usage: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by absorbance at 280nm)
• Storage Buffer: Liquid in. Phosphate-Buffered Saline (pH 7.4)

Gene Information

• Gene Name: SIGLEC5 sialic acid binding Ig like lectin 5 [ Homo sapiens (human) ]
• Official Symbol: SIGLEC5
• Synonyms: Sialic acid-binding Ig-like lectin 5, SIGLEC5, CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5
• Gene ID: 8778
• mRNA Refseq: NM_003830.4
• Protein Refseq: NP_003821.1
• MIM: 604200
• UniProt ID: O15389