Recombinant Human SIGIRR Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SIGIRR-1685H
• Product Overview: SIGIRR MS Standard C13 and N15-labeled recombinant protein (NP_068577) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: SIGIRR (Single Ig And TIR Domain Containing) is a Protein Coding gene. Diseases associated with SIGIRR include Central Nervous System Tuberculosis and Progressive Myoclonus Epilepsy 8. Among its related pathways are Activated TLR4 signalling and Innate Immune System. An important paralog of this gene is IL1RAPL2.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 45.7 kDa
• AA Sequence: MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVRYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDMSGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SIGIRR single Ig and TIR domain containing [ Homo sapiens (human) ]
• Official Symbol: SIGIRR
• Synonyms: SIGIRR; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single Ig IL-1-related receptor; single immunoglobulin domain IL1R1 related; TIR8; toll/interleukin-1 receptor 8; single Ig IL-1R-related molecule; single immunoglobulin domain-containing IL1R-related protein; MGC110992
• Gene ID: 59307
• mRNA Refseq: NM_021805
• Protein Refseq: NP_068577
• MIM: 605478
• UniProt ID: Q6IA17