Recombinant Human SHBG protein, His-tagged

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Gene Information
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Description :	This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.
Source :	HEK293F
Species :	Human
Tag :	His
Form :	Freeze-dried powder
Molecular Mass :	Predicted Molecular Mass: 19.3kDa; Accurate Molecular Mass: 19kDa as determined by SDS-PAGE reducing conditions.
Protein length :	Gly224~His388
Endotoxin :	<1.0EU per 1ug (determined by the LAL method)
Purity :	> 60%
Characteristic :	Isoelectric point is 6.6.
Applications :	SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling
Stability :	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration :	200ug/mL
Storage buffer :	20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution :	Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Name	SHBG sex hormone binding globulin [ Homo sapiens (human) ]
Official Symbol	SHBG
Synonyms	SHBG; sex hormone binding globulin; ABP; SBP; TEBG; sex hormone-binding globulin; sex steroid-binding protein; testis-specific androgen-binding protein; testosterone-binding beta-globulin; testosterone-estradiol-binding globulin; testosterone-estrogen-binding globulin
Gene ID	6462
mRNA Refseq	NM_001040.4
Protein Refseq	NP_001031.2
UniProt ID	P04278