Recombinant Human SH3 Domain Binding Glutamic Acid-Rich Protein Like, His-tagged

• Cat.No.: SH3BGRL-6952H
• Product Overview: Recombinant human SH3BGRL protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Specification

• Description: SH3BGRL is a member of the human SH3BGR family. SH3BGRL gene located to chromosome Xq13.3 encodes for a small protein of 114 amino acids, which is apparently widely expressed in many tissues including liver and blood. SH3BGRL protein features a prolinerich sequence (PLPPQIF), which contains both the SH3 binding (PXXP)3 and the Homer EVH1 binding (PPXXF)4 motif.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.15M NaCl.
• Molecular Mass: 15.3 kDa (138aa), confirmed by MALDI-TOF
• Protein length: 1-114aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVIRVY IASSSGSTAI KKKQQDVLGF LEANKIGFEE KDIAANEENR KWMRENVPEN SRPATGYPLP PQIFNESQYR GDYDAFFEAR ENNAVYAFLG LTAPPGSKEA EVQAKQQA
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SH3BGRL SH3 domain binding glutamic acid-rich protein like [ Homo sapiens ]
• Official Symbol: SH3BGRL
• Synonyms: SH3BGRL; SH3 domain binding glutamic acid-rich protein like; SH3 domain-binding glutamic acid-rich-like protein; MGC117402; SH3-binding domain glutamic acid-rich protein like; SH3BGR
• Gene ID: 6451
• mRNA Refseq: NM_003022
• Protein Refseq: NP_003013
• MIM: 300190
• UniProt ID: O75368
• Chromosome Location: Xq13.3
• Pathway: EGFR1 Signaling Pathway, organism-specific biosystem
• Function: SH3 domain binding; SH3/SH2 adaptor activity