Recombinant Human SGSH, MYC/DDK-tagged
Cat.No. : | SGSH-279H |
Product Overview : | Recombinant Human SGSH fused with C-terminal MYC/DDK, was expressed in HEK293 Cells. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. |
Molecular Mass : | 54.6 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Storagebuffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage : | Store at -800C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
OfficialSymbol : | SGSH |
Gene Name | SGSH N-sulfoglucosamine sulfohydrolase [ Homo sapiens ] |
Synonyms | SGSH; N-sulfoglucosamine sulfohydrolase; HSS; MPS3A; mucopolysaccharidosis type IIIA; SFMD; sulfamidase; heparan sulfate sulfatase; sulfoglucosamine sulfamidase; N-sulphoglucosamine sulphohydrolase; EC 3.10.1.1; Sulfoglucosamine sulfamidase; Sulphamidase |
Gene ID | 6448 |
mRNA Refseq | NM_000199 |
Protein Refseq | NP_000190 |
MIM | 605270 |
UniProt ID | P51688 |
Chromosome Location | 17q25.3 |
Pathway | Glycosaminoglycan degradation; Heparan sulfate degradation; Lysosome; MPS I - Hurler syndrome |
Function | N-sulfoglucosamine sulfohydrolase activity; catalytic activity; metal ion binding; sulfuric ester hydrolase activity |
◆ Recombinant Proteins | ||
SGSH-301590H | Recombinant Human SGSH protein, GST-tagged | +Inquiry |
SGSH-195H | Recombinant Human SGSH protein, His-tagged | +Inquiry |
SGSH-695H | Recombinant Human SGSH Protein, His/GST-tagged | +Inquiry |
SGSH-6275H | Recombinant Human SGSH Protein (Arg21-Leu502), C-His tagged | +Inquiry |
Sgsh-5829M | Recombinant Mouse Sgsh Protein, Myc/DDK-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
SGSH-1884HCL | Recombinant Human SGSH 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All SGSH Products
Required fields are marked with *
My Review for All SGSH Products
Required fields are marked with *
0
Inquiry Basket