Recombinant Human SGCA protein, His & GST-tagged

Cat.No. : SGCA-1669H
Product Overview : Recombinant Human SGCA aa. (Gln24~His387 (Accession # Q16586)) fused with N-terminal His & GST tag was produced in E. coli cells.
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Species : Human
Source : E.coli
Tag : GST&His
Protein Length : Gln24~His387
Description : This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 70.4kDa
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Isoelectric Point : 5.7
Gene Name SGCA sarcoglycan alpha [ Homo sapiens (human) ]
Official Symbol SGCA
Synonyms SGCA; sarcoglycan alpha; ADL; DAG2; 50DAG; DMDA2; LGMD2D; SCARMD1; adhalin; alpha-sarcoglycan; 50 kDa dystrophin-associated glycoprotein; 50kD DAG; alpha-SG; dystroglycan-2; limb girdle muscular dystrophy 2D; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Gene ID 6442
mRNA Refseq NM_000023.3
Protein Refseq NP_000014.1
UniProt ID Q16586

Not For Human Consumption!

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