Recombinant Human SFTPD, His-tagged

• Cat.No.: SFTPD-238H
• Product Overview: SFTPD, 224-375aa, Human, His tag, E.coli

Specification

• Description: SFTPD, as known as Surfactant pulmonary-associated protein D, is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. It is humoral molecules of the innate immune system, and is considered a functional candidate in chronic periodontitis. Besides it is involved in the development of acute and chronic inflammation of the lung. Several human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. Recombinant human SFTPD protein, fused to His-tag at N-terminus, was expressed in E.coli
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 18.9 kDa (175aa)
• Protein length: 224-375aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSVASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SFTPD surfactant protein D [ Homo sapiens ]
• Official Symbol: SFTPD
• Synonyms: SFTPD; surfactant protein D; SFTP4, surfactant, pulmonary associated protein D; pulmonary surfactant-associated protein D; COLEC7; SP D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4; SP-D; PSP-D; SFTP4
• Gene ID: 6441
• mRNA Refseq: NM_003019
• Protein Refseq: NP_003010
• MIM: 178635
• UniProt ID: P35247
• Chromosome Location: 10q22.2-q23.1
• Pathway: FOXA1 transcription factor network, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; Regulation of retinoblastoma protein, organism-specific biosystem
• Function: bacterial cell surface binding; protein binding; sugar binding