Recombinant Human SCO1 protein, His-tagged

• Cat.No.: SCO1-167H
• Product Overview: Recombinant Human SCO1(132-301aa) fused with His tag at C-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 132-301 a.a.
• Description: Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene.
• Form: Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT
• Molecular Mass: 20.5 kDa (179aa) confirmed by MALDI-TOF
• AA Sequence: MGKPLLGGPF SLTTHTGERK TDKDYLGQWL LIYFGFTHCP DVCPEELEKM IQVVDEIDSI TTLPDLTPLF ISIDPERDTK EAIANYVKEFSPKLVGLTGT REEVDQVARA YRVYYSPGPK DEDEDYIVDH TIIMYLIGPD GEFLDYFGQN KRKGEIAASI ATHMRPYRKK SLEHHHHHH
• Purity: > 95 % by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SCO1 SCO cytochrome oxidase deficient homolog 1 (yeast) [ Homo sapiens ]
• Official Symbol: SCO1
• Synonyms: SCO1; SCO cytochrome oxidase deficient homolog 1 (yeast); SCO (cytochrome oxidase deficient, yeast) homolog 1 , SCOD1; protein SCO1 homolog, mitochondrial; SCOD1
• Gene ID: 6341
• mRNA Refseq: NM_004589
• Protein Refseq: NP_004580
• MIM: 603644
• UniProt ID: O75880
• Chromosome Location: 17p13.1
• Pathway: Electron Transport Chain, organism-specific biosystem
• Function: copper ion binding; metal ion binding