Recombinant Human SCN3B Protein, Fc-tagged

• Cat.No.: SCN3B-544H
• Product Overview: Recombinant human SCN3B (Q9NY72) extracellular domain (Met 1-Glu 159) was fused with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• ProteinLength: 1-159 a.a.
• Predicted N Terminal: Phe 23
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Molecular Mass: The recombinant human SCN3B/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 378 amino acids and has a predicted molecular mass of 42.5 kDa. The apparent molecular mass of the reduced monomer is approximately 50-55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >96 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: SCN3B sodium channel, voltage gated, type III beta subunit [ Homo sapiens ]
• Official Symbol: SCN3B
• Synonyms: SCNB3; ATFB16; BRGDA7; HSA243396; sodium channel, voltage-gated, type III, beta subunit; voltage-gated sodium channel beta-3 subunit
• Gene ID: 55800
• mRNA Refseq: NM_001040151
• Protein Refseq: NP_001035241
• MIM: 608214
• UniProt ID: Q9NY72
• Chromosome Location: 11q23.3
• Pathway: Axon guidance, organism-specific biosystem; Cardiac conduction, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem