Recombinant Human SAE1 Protein, MYC/DDK-tagged

• Cat.No.: SAE1-222H
• Product Overview: Recombinant human SAE1 protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Description: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 32.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SUMO1 activating enzyme subunit 1 [ Homo sapiens ]
• Official Symbol: SAE1
• Synonyms: AOS1; HSPC140; SUA1; UBLE1A
• Gene ID: 10055
• mRNA Refseq: NM_001145713.1
• Protein Refseq: NP_001139185.1
• MIM: 613294
• UniProt ID: Q9UBE0