Recombinant Human S100A1 protein, His & S-tagged

• Cat.No.: S100A1-555H
• Product Overview: Recombinant Human S100A1 (P23297) aa. (Met1~Ser94) fused with N-terminal His & S tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
• Source: E. coli
• Species: Human
• Tag: His&S
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16.3 kDa
• Protein length: Met1~Ser94
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Characteristic: The isoelectric point is 4.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4

Gene Information

• Gene Name: S100A1 S100 calcium binding protein A1 [ Homo sapiens (human) ]
• Official Symbol: S100A1
• Synonyms: S100A1; S100; S100A; S100-alpha; S100 calcium binding protein A1; protein S100-A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 alpha; S100 protein, alpha polypeptide
• Gene ID: 6271
• mRNA Refseq: NM_006271.1
• Protein Refseq: NP_006262.1
• UniProt ID: P23297