Recombinant Human RPS6KA2, GST-tagged, Active

• Cat.No.: RPS6KA2-426H
• Product Overview: Recombinant full-length human RPS6KA2 was expressed bybaculovirusin Sf9insect cells usingan N-terminal GST tag. MW=112kDa.

Specification

• Cat. No.: RPS6KA2-426H
• Description: RSK3 is a member of the RSK (ribosomal S6 kinase) family that encodes a 733-amino-acid protein with a unique N-terminal region containing a putative nuclear localization signal. RSK3 mRNA is widely expressed and is activated by growth factors, serum and phorbol ester. Upon stimulation, RSK3 translocates to the cell nucleus and phosphorylates nuclear proteins. RSK3 can bind to ERK1/2 and this association increases the duration of RSK3 activation.
• Source: Sf9 insect cells using baculovirus.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• nullValue_other: Long-term potentiation; MAPK signaling pathway; Neurotrophin signaling pathway; Progesterone-mediated oocyte maturation; mTOR signaling pathway; Signalling by NGF

Gene Information

• Gene Name: RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 [ Homo sapiens ]
• Synonyms: RPS6KA2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; RSK; HU-2; RSK3; p90-RSK3; pp90RSK3; MAPKAPK1C; S6K-alpha; S6K-alpha2; ribosomal S6 kinase 3; ribosomal protein S6 kinase alpha 2; EC 2.7.11.1
• Gene ID: 6196
• mRNA Refseq: NM_001006932
• Protein Refseq: NP_001006933
• MIM: 601685
• UniProt ID: Q15349
• Chromosome Location: 6q27
• Function: ATP binding; magnesium ion binding; nucleotide binding; protein binding; transferase activity; protein serine/threonine kinase activity