Recombinant Human ROR2, Fc-tagged, Biotinylated

• Cat.No.: ROR2-668H
• Product Overview: The recombinant human ROR2-Fc fusion is expressed as a 598 amino acid protein consisting of Glu34 - Gly403 region of ROR2 (Uniprot #Q01974) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.

Specification

• Source: Human cells
• Species: Human
• Tag: Fc
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Molecular Mass: Calculated molecular mass (kDa): 66.9; Estimated by SDS-PAGE under reducing condition (kDa): 75-85
• Endotoxin: <0.1 eu="" per="" 1="" μg="" of="" purified="" recombinant="" protein="" determined="" by="" the="" lal="">
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
• Protein length: 34-403 a.a.

Gene Information

• Gene Name: ROR2 receptor tyrosine kinase-like orphan receptor 2 [ Homo sapiens ]
• Official Symbol: ROR2
• Synonyms: ROR2; receptor tyrosine kinase-like orphan receptor 2; BDB, BDB1, NTRKR2; tyrosine-protein kinase transmembrane receptor ROR2; neurotrophic tyrosine kinase receptor-related 2; BDB; BDB1; NTRKR2; MGC163394
• Gene ID: 4920
• mRNA Refseq: NM_004560
• Protein Refseq: NP_004551
• MIM: 602337
• UniProt ID: Q01974
• Chromosome Location: 9q22
• Pathway: Noncanonical Wnt signaling pathway, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling network, organism-specific biosystem
• Function: ATP binding; Wnt-protein binding; frizzled binding; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity