Recombinant Human RNH1 Protein, MYC/DDK-tagged

• Cat.No.: RNH1-305H
• Product Overview: Recombinant Human RNH1, transcript variant 4, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RNH1 ribonuclease/angiogenin inhibitor 1 [ Homo sapiens ]
• Official Symbol: RNH1
• Synonyms: RNH1; ribonuclease/angiogenin inhibitor 1; ribonuclease/angiogenin inhibitor , RNH; ribonuclease inhibitor; RAI; placental RNase inhibitor; placental ribonuclease inhibitor; RNH; MGC4569; MGC18200; MGC54054
• Gene ID: 6050
• mRNA Refseq: NM_203385
• Protein Refseq: NP_976319
• MIM: 173320
• UniProt ID: P13489