Recombinant Human Ribosomal Protein S7, His-tagged

• Cat.No.: RPS7-6858H
• Product Overview: Recombinant human RPS7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 24.7 kDa.

Specification

• Description: RPS7 belongs to the S3P family of ribosomal proteins and is located in the cytoplasm. RPS7 may play a role in ribosomal stress, linking ribosome biogenesis to cell death or cell cycle arrest. Also, RPS7 interacts with MDM2 and is believed to negatively regulate the MDM2-mediated degradation of p53.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol, 1mM DTT.
• Molecular Mass: 24.7 kDa (218aa), confirmed by MALDI-TOF.
• Protein length: 1-194aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMFSSSA KIVKPNGEKP DEFESGISQA LLELEMNSDL KAQLRELNIT AAKEIEVGGG RKAIIIFVPV PQLKSFQKIQ VRLVRELEKK FSGKHVVFIA QRRILPKPTR KSRTKNKQKR PRSRTLTAVH DAILEDLVFP SEIVGKRIRV KLDGSRLIKV HLDKAQQNNV EHKVETFSGV YKKLTGKDVN FEFPEFQL
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RPS7 ribosomal protein S7 [ Homo sapiens ]
• Official Symbol: RPS7
• Synonyms: RPS7; ribosomal protein S7; 40S ribosomal protein S7; S7; DBA8
• Gene ID: 6201
• mRNA Refseq: NM_001011
• Protein Refseq: NP_001002
• MIM: 603658
• UniProt ID: P62081
• Chromosome Location: 2p25
• Pathway: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem; Disease, organism-specific biosystem; Eukaryotic Translation Elongation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Eukaryotic Translation Termination, organism-specific biosystem
• Function: RNA binding; protein binding; structural constituent of ribosome