Recombinant Human Ribosomal Protein, Large, P2, His-tagged

• Cat.No.: RPLP2-5550H
• Product Overview: Recombinant humanRPLP2 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques.

Specification

• Cat. No.: RPLP2-5550H
• Description: 60S acidic ribosomalprotein P2,also known as RPLP2, belongs to the L12P family of ribosomal proteins. Thisgene encodes a ribosomal phosphoprotein that is a component of the 60Ssubunit. It is a functional equivalent of the E. coli L7/L12 ribosomalprotein. RPLP2 is located in the cytoplasm. It plays an important role in theelongation step of protein synthesis. Unlike most ribosomal proteins, whichare basic, the encoded protein is acidic.
• Source: E. coli
• Species: Human
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl.
• Molecular Weight: 14.2 kDa (139aa) confirmedby MALDI-TOF.
• Purity: > 95% by SDS -PAGE.
• Concentration: 1 mg/ml (determinedby Bradford assay).
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMRYVAS YLLAALGGNS SPSAKDIKKI LDSVGIEADD DRLNKVISEL NGKNIEDVIAQGIGKLASVP AGGAVAVSAA PGSAAPAAGS APAAAEEKKD EKKEESEESD DDMGFGLFD
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°Cor -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: RPLP2
• Pathways: Cap-dependentTranslation Initiation; Cytoplasmic Ribosomal Proteins; DevelopmentalBiology; Diabetes pathways; Eukaryotic Translation Elongation; EukaryoticTranslation Initiation; Formation of a pool of free 40S subunits; GTPhydrolysis and joining of the 60S ribosomal subunit; Gene Expression;Influenza Life Cycle; Insulin Synthesis and Processing; Metabolism;Metabolism of mRNA; Nonsense Mediated Decay Enhanced by the Exon JunctionComplex; Peptide chain elongation; Ribosome

Gene Information

• Gene Name: RPLP2 ribosomal protein, large,P2 [ Homo sapiens ]
• Synonyms: RPLP2; ribosomalprotein, large, P2; P2; LP2; RPP2; D11S2243E; 60S acidic ribosomal protein P2;renal carcinoma antigen NY-REN-44; acidic ribosomal phosphoprotein P2
• Gene ID: 6181
• mRNA Refseq: NM_001004
• Protein Refseq: NP_000995
• MIM: 180530
• UniProt ID: P05387
• Chromosome Location: 11p15.5
• Function: RNA binding;structural constituent of ribosome