Recombinant Human RGS6 Protein, His&GST-tagged

• Cat.No.: RGS6-2016H
• Product Overview: Recombinant Human RGS6 Protein (Met1-Glu127) with N-His&GST tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Met1-Glu127
• Description: This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 44.1 kDa
  Accurate Molecular Mass: 44 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: RGS6 regulator of G-protein signaling 6 [ Homo sapiens (human) ]
• Official Symbol: RGS6
• Synonyms: RGS6; regulator of G-protein signaling 6; regulator of G protein signalling 6; S914; H_DJ1108A12.1; WUGSC:H_DJ0283M22.1; WUGSC:H_DJ1108A12.1; GTPase activating protein; regulator of G-protein signalling 6; GAP; FLJ43552; MGC142132; DKFZp313G1241
• Gene ID: 9628
• mRNA Refseq: NM_001204416
• Protein Refseq: NP_001191345
• MIM: 603894
• UniProt ID: P49758