Recombinant Human RGS2, T7-tagged

• Cat.No.: RGS2-2979H
• Product Overview: Recombinant Human RGS2 (1-211 aa) is expressed inE.Coliwith a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-211 a.a.
• Description: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
• MW: 24382 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
• Application: MS. SDS.

Gene Information

• Gene Name: RGS2 regulator of G-protein signaling 2, 24kDa [ Homo sapiens ]
• Synonyms: RGS2; regulator of G-protein signaling 2, 24kDa; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; regulator of G-protein signaling 2; GIG31; G0S8
• Gene ID: 5997
• mRNA Refseq: NM_002923
• Protein Refseq: NP_002914
• MIM: 600861
• UniProt ID: P41220
• Chromosome Location: 1q31
• Function: GTPase activator activity; calmodulin binding; protein binding; signal transducer activity