Recombinant Human RGS2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RGS2-4015H
• Product Overview: RGS2 MS Standard C13 and N15-labeled recombinant protein (NP_002914) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
• Molecular Mass: 24.4 kDa
• AA Sequence: MQSAMFLAVQHDCRPMDKSAGSGHKSEEKREKMKRTLLKDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHATTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RGS2 regulator of G protein signaling 2 [ Homo sapiens (human) ]
• Official Symbol: RGS2
• Synonyms: RGS2; regulator of G-protein signaling 2, 24kDa; G0S8, regulator of G protein signalling 2, 24kD, regulator of G protein signalling 2, 24kDa; regulator of G-protein signaling 2; G0/G1 switch regulatory protein 8; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; cell growth-inhibiting gene 31 protein; G0S8
• Gene ID: 5997
• mRNA Refseq: NM_002923
• Protein Refseq: NP_002914
• MIM: 600861
• UniProt ID: P41220