Recombinant Human RETN, Flag-tagged

• Cat.No.: RETN-196H
• Product Overview: Recombinant Human RETN(aa 20-108), fused at the N-terminus to a FLAG-tag, was expressed in HEK 293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Description: This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Form: Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
• Bio-activity: Inhibits insulin-stimulated glucose uptake in L6 skeletal muscle cells.
• Molecular Mass: ~12kDa (SDS-PAGE)
• Endotoxin: <0.1EU/μg purified protein (LAL test; Lonza).
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°CLong Term Storage: -20°CHandling Advice: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: RETN resistin [ Homo sapiens (human) ]
• Official Symbol: RETN
• Synonyms: RETN; Cysteine-rich secreted protein; FIZZ3; Adipose tissue-specific secretory factor (ADSF); C/EBP-epsilon; regulated myeloid-sepcific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like-2; ADSF; MGC126603; MGC126609; RETN1; XCP1; resistin; MGC126609; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; Adipose tissue-specific secretory factor; C/EBP-epsilon regulated myeloid-specific secreted; cysteine-rich protein precursor 1; cysteine-rich protein; Cysteine-rich secreted protein FIZZ3; found in inflammatory zone 3
• Gene ID: 56729
• mRNA Refseq: NM_020415
• Protein Refseq: NP_065148
• MIM: 605565
• UniProt ID: Q9HD89
• Chromosome Location: 19p13.2
• Pathway: Adipogenesis
• Function: hormone activity