Recombinant Human Reticulocalbin 3, EF-Hand Calcium Binding Domain, His-tagged

• Cat.No.: RCN3-5548H
• Product Overview: Recombinanthuman RCN3protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventionalchromatography techniques.

Specification

• Cat. No.: RCN3-5548H
• Description: RCN3 is a member of the CREC (cab45/reticulocalbin/ERC45/calumenin) family. RCN3 contains five Arg-Xaa-Xaa-Arg motifs,which function as target sequences of SPCs (subtilisin-like proproteinconvertases), a family of serine endoproteases that proteolytically activateproproteins. The synthesis of one such member, PACE4 (paired basic amino acidcleaving enzyme 4), is influenced by association and coexpression withreticulocalbin-3.
• Form: Liquid.In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl.
• Molecular Weight: 37.9 kDa(333aa) confirmed by MALDI-TOF
• Purity: > 95%by SDS-PAGE
• Concentration: 1 mg/ml (determinedby Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMKPSPD AGPHGQGRVH QAAPLSDAPH DDAHGNFQYDHEAFLGREVA KEFDQLTPEE SQARLGRIVD RMDRAGDGDGWVSLAELRAW IAHTQQRHIR DSVSAAWDTY DTDRDGRVGW EELRNATYGH YAPGEEFHDV EDAETYKKMLARDERRFRVA DQDGDSMATR EELTAFLHPE EFPHMRDIVI AETLEDLDRN KDGYVQVEEY IADLYSAEPGEEEPAWVQTE RQQFRDFRDL NKDGHLDGSE VGHWVLPPAQDQPLVEANHL LHESDTDKDG RLSKAEILGN WNMFVGSQAT NYGEDLTRHH DEL
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoidrepeated freezing and thawing cycles.

Gene Information

• Gene Name: RCN3 reticulocalbin 3, EF-handcalcium binding domain [ Homo sapiens ]
• Official Symbol: RCN3
• Synonyms: RCN3; reticulocalbin3, EF-hand calcium binding domain; RLP49; reticulocalbin-3;reticulocabin; EF-hand calcium-binding protein RLP49
• Gene ID: 57333
• mRNA Refseq: NM_020650
• Protein Refseq: NP_065701
• UniProt ID: Q96D15
• Chromosome Location: 19q13.33
• Function: calciumion binding; protein binding