Recombinant Human Resistin
Cat.No. : | RETN-70H |
Product Overview : | Recombinant Human Resistin is a 9.9 kDa protein containing 93 amino acid residues. It was expressed in E.coli. ASSKTLCSME EAINERIQEV AGSLIFRAIS SIGLECQSVT SRGDLATCPR GFAVTGCTCG SACGSWDVRA ETTCHCQCAG MDWTGARCCR VQP. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | Resistin, a product of the RSTN gene, is a peptide hormone belonging to the class of cysteine-rich secreted proteins which is termed the RELM family, and is also described as ADSF (Adipose Tissue- Specific Secretory Factor) and FIZZ3 (Found in Inflammatory Zone). Human resistin contains 108 amino acids as a prepeptide, and its hydrofobic signal peptide is cleaved before its secretion. Resistin circulates in human blood as a dimeric protein consisting of two 92 amino acid polypeptides, which are disulfide-linked via Cys26. Resistin may be an important link between obesity and insulin resistance. |
Specificity : | The amino acid sequence of the Resistin Human Recombinant is homologous to the amino acid sequence of the Resistin Human without signal sequence. |
Purification Method : | Two-step procedure using size exclusion chromatography before and after refolding. |
Purity : | >98% (SDS-PAGE analyzed). |
Formulation : | Recombinant Human Resistin was lyophilized from a concentrated (1 mg/ml) solution containg 0.03% NaHCO3. |
Solubility : | Add 0.2 ml of deionized water and let the lyophilized pellet dissolve completely. |
Specific Activity : | The biological activity was evidenced by the Resistin ability to prevent insulin-stimulated uptake of deoxy glucose in several cell lines at 10 ng/ml concentration. |
Stability : | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. The lyophilized protein remains stable until the expiry date when stored at -20°C. |
Gene Name | RETN resistin [ Homo sapiens ] |
Synonyms | RETN; resistin; ADSF; RSTN; XCP1; MGC126603; MGC126609; found in inflammatory zone 3;C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; HXCP1; Adipose tissue-specific secretory factor; FIZZ3; RETN1; C/EBP-epsilon-regulated myeloid-specific secretedcysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3 |
Gene ID | 56729 |
mRNA Refseq | NM_020415 |
Protein Refseq | NP_065148 |
MIM | 605565 |
UniProt ID | Q9HD89 |
Chromosome Location | 19p13.2 |
Function | hormone activity |
◆ Recombinant Proteins | ||
RETN-18H | Recombinant Human RETN protein, MYC/DDK-tagged | +Inquiry |
Retn-69R | Recombinant Rat Resistin, His-tagged | +Inquiry |
RETN-7821P | Recombinant Pig RETN protein, His & T7-tagged | +Inquiry |
Retn-5477H | Active Recombinant Mouse Retn protein | +Inquiry |
RETN-196H | Recombinant Human RETN, Flag-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
RETN-1635MCL | Recombinant Mouse RETN cell lysate | +Inquiry |
Not For Human Consumption!
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