Recombinant Human Renalase, FAD-Dependent Amine Oxidase, His-tagged

• Cat.No.: RNLS-7164H
• Product Overview: Recombinant human RNLS protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 38.8 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 18-342aa
• Description: Renalase, also known as RNLS, is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. It is also suggested that RNLS functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. A high concentration of catecholamines activate plasma RNLS and promotes its secretion and synthesis.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 10% glycerol.
• Molecular Mass: 38.8 kDa (349aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMALLRRQ TSGPLYLAVW DKAEDSGGRM TTACSPHNPQ CTADLGAQYI TCTPHYAKKH QRFYDELLAY GVLRPLSSPI EGMVMKEGDC NFVAPQGISS IIKHYLKESG AEVYFRHRVT QINLRDDKWE VSKQTGSPEQ FDLIVLTMPV PEILQLQGDI TTLISECQRQ QLEAVSYSSR YALGLFYEAG TKIDVPWAGQ YITSNPCIRF VSIDNKKRNI ESSEIGPSLV IHTTVPFGVT YLEHSIEDVQ ELVFQQLENI LPGLPQPIAT KCQKWRHSQV TNAAANCPGQ MTLHHKPFLA CGGDGFTQSN FDGCITSALC VLEALKNYI
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RNLS renalase, FAD-dependent amine oxidase [ Homo sapiens ]
• Official Symbol: RNLS
• Synonyms: RNLS; renalase, FAD-dependent amine oxidase; C10orf59, chromosome 10 open reading frame 59; renalase; FLJ11218; MAO-C; monoamine oxidase-C; C10orf59; RENALASE
• Gene ID: 55328
• mRNA Refseq: NM_001031709
• Protein Refseq: NP_001026879
• MIM: 609360
• UniProt ID: Q5VYX0
• Chromosome Location: 10q23.31
• Function: oxidoreductase activity