Recombinant Human RCN2 protein, His-tagged

• Cat.No.: RCN2-257H
• Product Overview: Recombinant Human Reticulocalbin-2 is produced by our Mammalian expression system and the target gene encoding Gly23-Leu317 is expressed with a 6His tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Gly23-Leu317
• Description: Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 could be a potential tumor-associated antigen for mammary cancer immunological prevention. Up to now, the experimental evidence uncovering the role of RCN2 in cancer is very limited.
• Form: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, 1mM DTT, pH 8.0.
• Molecular Mass: 50-55kDa, reducing conditions.
• Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Store at < -20°C, stable for 6 months after receipt.
  Please minimize freeze-thaw cycles.
• Shipping: The product is shipped on dry ice/polar packs.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: RCN2 reticulocalbin 2 [ Homo sapiens (human) ]
• Official Symbol: RCN2
• Synonyms: Reticulocalbin-2; RCN2; E6BP; ERC55
• Gene ID: 5955
• mRNA Refseq: NM_001271837.2
• Protein Refseq: NP_001258766.1
• MIM: 602584
• UniProt ID: Q14257