Recombinant Human Ras-related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2), GST-tagged

• Cat.No.: RAC2-343H
• Product Overview: Recombinant GST tagged RAC2 was expressed in E.coli and purified by using conventional chromatography techniques (419 aa, 47 kDa).

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: Rac2 is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. Rac proteins play important roles in multiple cellular events, including actin cytoskeletal organization, cell proliferation and survival, cell cycle progression, and gene transcription regulation.
• Formulation: Liquid. In Phosphate Buffered Saline( pH 7.4).
• Molecular Weight: 47 kDa (419 aa).
• Purity: > 90% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMQA IKCVVVGDGA VGKTCLLISY TTNAFPGEYI PTVFDNYSAN VMVDSKPVNL GLWDTAGQED YDRLRPLSYP QTDVFLICFS LVSPASYENV RAKWFPEVRH HCPSTPIILV GTKLDLRDDK DTIEKLKEKK LAPITYPQGL ALAKEIDSVK YLECSALTQR GLKTVFDEAI RAVLCPQPTR QQKRACSLL
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAC2
• Synonyms: RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Gx; EN-7; HSPC022; GX; p21-Rac2; Small G protein; ras-related C3 botulinum toxin substrate 2; rho family, small GTP binding protein Rac2; RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2).
• Gene ID: 5880
• mRNA Refseq: NM_002872.3
• Protein Refseq: NP_002863.1
• MIM: 602049
• UniProt ID: P15153
• Chromosome Location: 22q13.1
• Pathway: Adherens junction; Axon guidance; B cell receptor signaling pathway; Colorectal cancer; Fc epsilon RI signaling pathway; Focal adhesion; Leukocyte transendothelial migration; MAPK signaling pathway; Natural killer cell mediated cytotoxicity; Pancreatic cancer; Regulation of actin cytoskeleton; VEGF signaling pathway; Wnt signaling pathway; Signaling by Rho GTPases.
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding.