Recombinant Human RAD52 Protein, MYC/DDK-tagged

• Cat.No.: RAD52-682H
• Product Overview: Recombinant Human RAD52, transcript variant 3, fused with MYC/DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
• Source: HEK293 cell
• Species: Human
• Tag: Myc&DDK
• Form: 25mM Tris-HCl, pH 7.3, 100mM glycine, and 10% glycerol.
• Molecular Mass: 46 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RAD52 RAD52 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: RAD52
• Synonyms: RAD52; RAD52 homolog (S. cerevisiae); RAD52 (S. cerevisiae) homolog; DNA repair protein RAD52 homolog; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23
• Gene ID: 5893
• mRNA Refseq: NM_134424
• Protein Refseq: NP_602296
• MIM: 600392
• UniProt ID: P43351