Recombinant Full Length Human RAB7A Protein, His-tagged

• Cat.No.: RAB7A-2649H
• Product Overview: Recombinant Human RAB7A Protein (Thr2-Cys207) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Thr2-Cys207
• Description: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.1 kDa
  Accurate Molecular Mass: 27 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: RAB7A RAB7A, member RAS oncogene family [ Homo sapiens (human) ]
• Official Symbol: RAB7A
• Synonyms: RAB7A; RAB7A, member RAS oncogene family; RAB7, RAB7, member RAS oncogene family; ras-related protein Rab-7a; Ras-associated protein RAB7; RAB7, member RAS oncogene family; RAB7; PRO2706; FLJ20819
• Gene ID: 7879
• mRNA Refseq: NM_004637
• Protein Refseq: NP_004628
• MIM: 602298
• UniProt ID: P51149