Recombinant Human PTX3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PTX3-463H
• Product Overview: PTX3 MS Standard C13 and N15-labeled recombinant protein (NP_002843) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 41.8 kDa
• AA Sequence: MHLLAILFCALWSAVLAENSDDYDLMYVNLDNEIDNGLHPTEDPTPCDCGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVSTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PTX3 pentraxin 3 [ Homo sapiens (human) ]
• Official Symbol: PTX3
• Synonyms: PTX3; pentraxin 3, long; pentaxin related gene, rapidly induced by IL 1 beta, pentraxin related gene, rapidly induced by IL 1 beta, TNFAIP5, tumor necrosis factor, alpha induced protein 5; pentraxin-related protein PTX3; TSG 14; pentraxin-3; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor necrosis factor-inducible gene 14 protein; pentraxin-related gene, rapidly induced by IL-1 beta; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5; TSG-14; TNFAIP5
• Gene ID: 5806
• mRNA Refseq: NM_002852
• Protein Refseq: NP_002843
• MIM: 602492
• UniProt ID: P26022