Recombinant Human PTGDS Protein, GST-tagged

• Cat.No.: PTGDS-54H
• Product Overview: Recombinant human PTGDS protein with a N-terminal GST-tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
• Molecular Mass: 46 kDa
• Purity: ≥85% estimated by SDS-PAGE
• Stability: ≥ 2 years
• Storage: Store it at -80 centigrade
• Storage Buffer: 50 mM sodium phosphate, pH 7.2, containing 20% glycerol, 150 mM sodium chloride, 1 mM DTT, and 0.5 mM EDTA

Gene Information

• Gene Name: PTGDS prostaglandin D2 synthase [ Homo sapiens (human) ]
• Official Symbol: PTGDS
• Synonyms: PTGDS; prostaglandin D2 synthase; PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS; prostaglandin-H2 D-isomerase; PGD2 synthase; beta-trace protein; cerebrin-28; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; prostaglandin D synthase; prostaglandin D2 synthase 21kDa (brain); testis tissue sperm-binding protein Li 63n
• Gene ID: 5730
• mRNA Refseq: NM_000954
• Protein Refseq: NP_000945
• MIM: 176803
• UniProt ID: P41222